Microphysiological Systems Technology Hub

Commercially available microphysiological systems.

Microphysiological Systems (MPS) are in vitro models composed of cells, tissue explants, or stem-cell derived ‘organoid’ formations of human or animal origin. These models provide translational biochemical, electrical, and/or physiomechanical responses to represent organ and tissue function, with great potential to replace some animals used in research.

Below you can explore Microphysiological System Companies offering commercially available advanced in vitro models across a variety of organs as well as enabling technologies. This includes organ-on-a-chip, organoid, and spheroid companies. Individual technology providers may offer products or services, share key publications, and encourage contact and questions via the outreach buttons.

To learn more about a particular organ system, check out our MPS presentation page. So far we’ve hosted presentations on liver, kidney, neuro, blood-brain-barrier, and vascular MPS.

Tissues Offered

Tissues Offered
  • BBB (7)
  • Bone Marrow (2)
  • Cartilage (2)
  • CNS & Neuro (13)
  • Fat (2)
  • Gut (9)
  • Heart (3)
  • Kidney (7)
  • Liver (11)
  • Lung (6)
  • Multi-Organ (7)
  • Ocular (1)
  • Pancreas (3)
  • Reproductive (2)
  • Skeletal Muscle (5)
  • Skin (3)
  • Tumor (14)
  • Vasculature (10)

Disease Area Offered

Disease Area Offered
  • Diabetes (1)
  • Fibrosis (2)
  • Metabolic Disease (6)
  • Microbiome (1)
  • Neurodegenerative Disease (1)
  • Neurological Disease (5)
  • Neuromuscular Disease (1)
  • Toxicology (4)

Non-Human Species

Non-Human Species
  • Dog (1)
  • Mouse (1)
  • Non-Human Primate (1)
  • Pig (1)
  • Rat (2)
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Enabling Technologies

Enabling technologies are complementary tools to help end users perform experiments with MPS platforms or extract data from them. These technologies are only applicable to certain MPS depending on the organ model and the technology used in the platform.


Our high-throughput histology platform, SpheroMatrices®, aligns MPS/organoids from plate-based experiments  in a single plane in a microscope slide-sized  microTMA format, retaining the plate layout. All tissues within the microTMA are wax embedded and simultaneously sectioned into parallel sections for downstream analysis via histopathology, immunostaining, and /or transcript profiling.

Contact MicroMatrices