Advanced microfluidic technologies for Nanomedicine Development. We develop and employ human microphysiological systems or organ-on-a-chip to better predict drug toxicity and efficacy.
Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
This study assesses the developmental neurotoxicity of paroxetine—a widely used SSRI which has shown contradictory evidence regarding effects on human brain development using a versatile, organotypic human induced pluripotent stem cell (iPSC)-derived brain model (BrainSpheres).
For more than a decade, Ncardia has been pioneering innovations in human induced pluripotent stem cells (iPSC).
Ananda Devices is a biotech company offering high throughput organ on-a-chip technologies such as neurons on-a-chip to accelerate R&D in pharmaceutical, food and cosmetic (PFC) industries
Stem Pharm offers functional 2-D and 3-D human tissue models for disease modeling, drug discovery, and toxicity screening. We specialize in neural organoid and vascular models. Our team of scientists can also help users identify and develop unique synthetic hydrogels for their own MPS needs.
Emulate develops a breadth of Organ-Chip models with a focus on recreating the microenvironment and mechanical forces cells experience in vivo. Hardware automating media flow and stretch, Bio-Kits including chips and qualified human cells, and a range of standard and custom services are available.
Hesperos is accelerating drug discovery by providing safety and efficacy testing services using its Human-on-a-Chip, microphysiological system. This breakthrough technology enables unprecedented preclinical insight bringing better therapies to patients faster without the need for animal testing.
CN Bio is a leading bioengineering company specializing in single and multi-organ microphysiological systems and innovative lab technologies. We aim to provide systems that generate clinically translatable data that can enhance the development of tomorrow’s medicines.
Mimetas develops high-throughput healthy and diseased organ-on-a-chip models in the OrganoPlate®, a screening-compatible microfluidics platform that supports the recreation of native tissue structures, and their interaction with compounds, signaling factors, disease triggers, and co-cultured cell types.